Cardiovascular Mortality in Women With Obstructive Sleep Apnea With or Without Continuous Positive Airway Pressure Treatment

Letters5 June 2012Cardiovascular Mortality in Women With Obstructive Sleep Apnea With or Without Continuous Positive Airway Pressure TreatmentThomas E. Finucane, MDThomas E. Finucane, MDFrom Johns Hopkins University School of Medicine, Baltimore, MD 21224.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-156-11-201206050-00012 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:In 1980, the Coronary Drug Project (1) showed that among patients assigned to placebo, those who faithfully (at least 80% of the time) took the lactose placebo had a roughly 50% reduction in death compared with those who took the pill less faithfully. The authors note “the serious difficulty, if not impossibility, of evaluating treatment efficacy in subgroups determined by patient ... adherence ....” Adherent patients seem different from nonadherent patients in ways that are difficult to characterize.Campos-Rodriguez and colleagues (2) compared cardiovascular mortality rates in women “with OSA [obstructive sleep apnea] [who] were classified as ...References1. Influence of adherence to treatment and response of cholesterol on mortality in the coronary drug project. N Engl J Med. 1980;303:1038-41. [PMID: 6999345] CrossrefMedlineGoogle Scholar2. Campos-Rodriguez F, Martinez-Garcia MA, de la Cruz-Moron I, Almeida-Gonzalez C, Catalan-Serra P, Montserrat JM. Cardiovascular mortality in women with obstructive sleep apnea with or without continuous positive airway pressure treatment: a cohort study. Ann Intern Med. 2012;156:115-22. [PMID: 22250142] LinkGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From Johns Hopkins University School of Medicine, Baltimore, MD 21224.Disclosures: None disclosed. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoCardiovascular Mortality in Women With Obstructive Sleep Apnea With or Without Continuous Positive Airway Pressure Treatment Francisco Campos-Rodriguez , Miguel A. Martinez-Garcia , Ines de la Cruz-Moron , Carmen Almeida-Gonzalez , Pablo Catalan-Serra , and Josep M. Montserrat Cardiovascular Mortality in Women With Obstructive Sleep Apnea With or Without Continuous Positive Airway Pressure Treatment Francisco Campos-Rodriguez and Miguel A. Martinez-Garcia Metrics 5 June 2012Volume 156, Issue 11Page: 838KeywordsConflicts of interestContinuous positive airway pressureDeath ratesDrugsLactoseSleep apnea ePublished: 5 June 2012 Issue Published: 5 June 2012 CopyrightCopyright © 2012 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...