多巴胺
被盖腹侧区
去抑制
神经科学
长时程增强
神经传递
神经元
突触可塑性
多巴胺摄取抑制剂
生物
化学
伏隔核
多巴胺能
生物化学
受体
作者
Christina Bocklisch,Vincent Pascoli,Jovi C Y Wong,David Richard Clermont House,Cédric Yvon,Mathias De Roo,Kelly R. Tan,Christian Lüscher
出处
期刊:Science
[American Association for the Advancement of Science (AAAS)]
日期:2013-09-27
卷期号:341 (6153): 1521-1525
被引量:259
标识
DOI:10.1126/science.1237059
摘要
Drugs, Dopamine, and Disinhibition Drugs often change the neuronal circuitry in the brain and thereby cause a long-lasting change in behavior. Using a wide range of in vivo and in vitro techniques in mice, Bocklisch et al. (p. 1521 ) observed that cocaine profoundly altered dopamine neuron function and that drug-evoked synaptic plasticity in a specific set of neurons represents a crucial step in circuit remodeling.
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