Evaluation on the Safety and Immunogenicity of Inactivated Influenza Vaccine (VAXIGRIP)

In order to recognize the safety and immunogenticity of influenza (flu) vaccine, especially the dose forms used for children, we carried out a study of the safety and immunogenicity of VAXIGRIP inoculated in children and adults in Tianjin at the end of 1999. A total of 53 adults (aged between 25～55 years old) and 69 children (aged between 6 months-3 years old) were included. The side-effect rates of adults and chilaren were 3.8% and 8.7% respectively, while the antibody positive seroconversion rates reached 92.2% and 85.8% respectively. The study showed that both the children dose form and the adult dose form of VAXIGRIP are with good immunogenicity and safety.