l-Threonine upregulates the expression of β-defensins by activating the NF-κB signaling pathway and suppressing SIRT1 expression in porcine intestinal epithelial cells

The study explores the effects of l-threonine on regulating β-defensin expression, alleviating LPS-induced intestinal mucosal barrier damage and reducing inflammatory cytokine expression in porcine intestinal epithelial cell lines (IPEC-J2).