巨细胞病毒
巨细胞病毒感染
免疫学
移植
重症监护医学
医学
器官移植
巨细胞病毒感染
疾病
免疫系统
感染控制
人类免疫缺陷病毒(HIV)
人巨细胞病毒
病毒性疾病
疱疹病毒科
病毒
内科学
作者
Ajit P. Limaye,Tara M Babu,Michael Boeckh
摘要
Hosts with compromised or naive immune systems, such as individuals living with HIV/AIDS, transplant recipients, and fetuses, are at the highest risk for complications from cytomegalovirus (CMV) infection. Despite substantial progress in prevention, diagnostics, and treatment, CMV continues to negatively impact both solid-organ transplant (SOT) and hematologic cell transplant (HCT) recipients. In this article, we summarize important developments in the field over the past 10 years and highlight new approaches and remaining challenges to the optimal control of CMV infection and disease in transplant settings.
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