微电极
接口
材料科学
生物医学工程
神经假体
神经活动
纳米技术
计算机科学
神经科学
电极
化学
工程类
计算机硬件
生物
物理化学
作者
Lei Gao,Jinfen Wang,Shouliang Guan,Mingde Du,Kun Wu,Ke Xu,Liang Zou,Huihui Tian,Ying Fang
出处
期刊:Nano Letters
[American Chemical Society]
日期:2019-10-03
卷期号:19 (11): 8032-8039
被引量:24
标识
DOI:10.1021/acs.nanolett.9b03232
摘要
Implantable microelectrodes that can be remotely actuated via external fields are promising tools to interface with biological systems at a high degree of precision. Here, we report the development of flexible magnetic microelectrodes (FMμEs) that can be remotely actuated by magnetic fields. The FMμEs consist of flexible microelectrodes integrated with dielectrically encapsulated FeNi (iron–nickel) alloy microactuators. Both magnetic torque- and force-driven actuation of the FMμEs have been demonstrated. Nanoplatinum-coated FMμEs have been applied for in vivo recordings of neural activities from peripheral nerves and cerebral cortex of mice. Moreover, owing to their ultrasmall sizes and mechanical compliance with neural tissues, chronically implanted FMμEs elicited greatly reduced neuronal cell loss in mouse brain compared to conventional stiff probes. The FMμEs open up a variety of new opportunities for electrically interfacing with biological systems in a controlled and minimally invasive manner.
科研通智能强力驱动
Strongly Powered by AbleSci AI