Methods:We conducted a systematic review of randomized controlled trials and quasi experimental studies, using the Joanna Briggs Institute methodology of systematic reviewing and PRISMA-P guidelines.Results: We identified 23 interventions that showed positive effects on one or more of the following psychosocial outcomes: depression, anxiety, fatigue, (health related) quality of life, hope, and (societal) participation.Interventions shown to be effective on one or more of these outcomes focused at least on the components: prevention of risk factors, self-management, recovery, coping, and mood, and included active information provision and physical activity.Conclusions: To effectively improve psychosocial well-being after stroke, this review confirms the value of a multicomponent intervention that focusses not only on clustered psychosocial consequences but also on stroke related problems.Such a multicomponent intervention requires further refinement / development and evaluation within the entire stroke care pathway.