接种疫苗
流行病模型
入射(几何)
理论(学习稳定性)
医学
病毒学
人口学
数学
统计
计算机科学
环境卫生
人口
社会学
几何学
机器学习
作者
Jicai Huang,Hao Kang,Min Lu,Shigui Ruan,Wenting Zhuo
标识
DOI:10.1016/j.nonrwa.2022.103525
摘要
Age structure of the host population is a crucial factor in the transmission and control of infectious diseases, since the risk from an infection increases along with age, different age groups interact heterogeneously, vaccination programs focus on specific age groups, and epidemiological data are reported according to ages. In this paper we consider an age-structured epidemic model of the susceptible–exposed–infectious–recovered (SEIR) type with vaccination and standard incidence rate. After establishing the well-posedness of the initial–boundary value problem, we study the existence and stability of the disease-free and endemic steady states based on the basic reproduction number R 0 . It is shown that the disease-free steady state is globally asymptotically stable if R 0 < 1 , the endemic steady state is unique if R 0 < 1 and is locally asymptotically stable under some additional conditions. Some numerical simulations are presented to illustrate the theoretical results.
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