医学
心房颤动
节奏
不利影响
重症监护医学
心脏病学
内科学
心力衰竭
心房颤动的处理
心律
烧蚀
作者
A. John Camm,Gerald V. Naccarelli,Suneet Mittal,Harry J.G.M. Crijns,Stefan H. Hohnloser,Changsheng Ma,Andrea Natale,Mintu P. Turakhia,Paulus Kirchhof
标识
DOI:10.1016/j.jacc.2022.03.337
摘要
The considerable mortality and morbidity associated with atrial fibrillation (AF) pose a substantial burden on patients and health care services. Although the management of AF historically focused on decreasing AF recurrence, it evolved over time in favor of rate control. Recently, more emphasis has been placed on reducing adverse cardiovascular outcomes using rhythm control, generally by using safe and effective rhythm-control therapies (typically antiarrhythmic drugs and/or AF ablation). Evidence increasingly supports early rhythm control in patients with AF that has not become long-standing, but current clinical practice and guidelines do not yet fully reflect this change. Early rhythm control may effectively reduce irreversible atrial remodeling and prevent AF-related deaths, heart failure, and strokes in high-risk patients. It has the potential to halt progression and potentially save patients from years of symptomatic AF; therefore, it should be offered more widely.
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