医学
信号转导
免疫系统
癌症研究
替代补体途径
免疫耐受
细胞生物学
计算生物学
免疫学
生物信息学
生物
补体系统
作者
Vassiliki A. Boussiotis
标识
DOI:10.1056/nejmra1514296
摘要
The PD-1 pathway plays an essential role in maintaining immunologic self-tolerance. However, cancers can subvert the role of this pathway and blind the immune system to their presence. The molecular details of the pathway are discussed.
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