For aircraft large thin-walled flexible fixture locating surface is small, insufficient clamping force, clamping rigidity is not enough, not suitable for milling, in order to solve the problem of cutting force and installation stiffness do not match, approximate surface developed the intelligent flexible process equipment support system.Using approximate surface orientation, local clamping.Through the analysis of system structure and operation principle, has established the mathematical model of the proposed adaptive optimization method such as curvature surface positioning.The method according to the given workpiece curvature, selection of curvature approximation of the bearing surface, adaptively adjust positioning/support distribution of flexible fixture system, guarantee the deformation reaching a minimum overall.Example shows that this method can make flexible fixture system supporting distribution in the optimal state, the clamping stiffness meet the requirements of milling, achieve the best utilization of resources, meet the demand of vehicle high speed and high precision machining of large thin wall parts.