Brain Stimulation, Learning, and Memory

Advances in electrophysiology and high-resolution brain imaging have improved our understanding of the neural circuitry of episodic memory, including differential contributions of the hippocampus and the rhinal cortices. These advances are timely: the aging of the human population makes the elucidation of memory mechanisms in aging and dementia an urgent priority for neuroscience and global health.In this context, neurosurgeons and multidisciplinary scientific teams engaged in deep-brain stimulation for clinical treatment are strategically positioned to provide invaluable insight into memory networks in action.1 Taking a cue from research in animals showing that stimulation of the entorhinal perforant pathway improves memory, . . .