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Letters16 July 2013Computed Tomography Screening for Lung CancerGuglielmo M. Trovato, MD, Marco Sperandeo, MD, and Daniela Catalano, MDGuglielmo M. Trovato, MDFrom University of Catania, Catania, Italy., Marco Sperandeo, MDFrom University of Catania, Catania, Italy., and Daniela Catalano, MDFrom University of Catania, Catania, Italy.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-159-2-201307160-00016 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Henschke and colleagues (1) suggest that a threshold of 7.0 or 8.0 mm to define positive results in the baseline round of computed tomography (CT) screening for lung cancer could decrease further work-up and a delay in diagnosis in some patients. Although nodule size is important, it is not the sole predictor of risk for cancer (2). In our experience, 70% of the pleural surface is accessible by transthoracic ultrasonography when the lung comes up to the pleura or is reachable via a sound window. Contrast-enhanced ultrasonography provides further information.In patients with lung cancer, we observed ...References1. Henschke CI, Yip R, Yankelevitz DF, and Smith JP; International Early Lung Cancer Action Program Investigators. Definition of a positive test result in computed tomography screening for lung cancer: a cohort study. Ann Intern Med. 2013;158:246-52 LinkGoogle Scholar2. Lam S, McWilliams A, Mayo J, and Tammemagi M. Computed tomography screening for lung cancer: what is a positive screen? [Editorial]. Ann Intern Med. 2013;158:289-90 LinkGoogle Scholar3. Sperandeo M, Sperandeo G, Varriale A, Filabozzi P, Decuzzi M, Dimitri L, et al. Contrast-enhanced ultrasound (CEUS) for the study of peripheral lung lesions: a preliminary study. Ultrasound Med Biol. 2006;32:1467-72. [PMID: 17045865] CrossrefMedlineGoogle Scholar4. Sperandeo M, Filabozzi P, Varriale A, Carnevale V, Piattelli ML, Sperandeo G, et al. Role of thoracic ultrasound in the assessment of pleural and pulmonary diseases. J Ultrasound. 2008;11:39-46. [PMID: 23396553] CrossrefMedlineGoogle Scholar5. Sperandeo M, Carnevale V, Muscarella S, Sperandeo G, Varriale A, Filabozzi P, et al. Clinical application of transthoracic ultrasonography in inpatients with pneumonia. Eur J Clin Invest. 2011;41:1-7. [PMID: 20731700] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAuthors: Guglielmo M. Trovato, MD; Marco Sperandeo, MD; Daniela Catalano, MDAffiliations: From University of Catania, Catania, Italy.Disclosures: Drs. Trovato and Catalano: Employment: University Hospital of Catania. Dr. Sperandeo: Employment: Hospital Casa Sollievo della Sofferenza IRCSS. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoDefinition of a Positive Test Result in Computed Tomography Screening for Lung Cancer Claudia I. Henschke , Rowena Yip , David F. Yankelevitz , and James P. Smith , for the International Early Lung Cancer Action Program Investigators* Computed Tomography Screening for Lung Cancer Peter B. Bach , Michael K. Gould , and Gerard A. Silvestri Computed Tomography Screening for Lung Cancer Claudia I. Henschke , Rowena Yip , David F. Yankelevitz , and James P. Smith Metrics 16 July 2013Volume 159, Issue 2Page: 155KeywordsBiopsyCancer screeningComputed axial tomographyDiagnostic radiologyInpatientsLesionsLung and intrathoracic tumorsLungsNecrosisPneumoniaPneumonitisStiffnessThoraxUltrasound imaging ePublished: 16 July 2013 Issue Published: 16 July 2013 Copyright & PermissionsCopyright © 2013 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...