Study on the effect of Gengning pills on perimenopausal syndrome in rats

OBJECTIVE To explore the principles of treatment for perimenopausal syndrome with Gengning pill.METHODS The effects of Gengning pill on the levels of FSH,LH,E2,TSH,TT3 and TT4 of ovariectomized rats were observed.RESULTS Compared with those of blank contrasts,Gengning pill could decrease the levels of FSH、LH、TT3、TT4 of ovariectomized rats distinctively(P0.05).Meanwhile,it candecrease the levels of TSH and increase the value of E2 of ovariectomized rats indistinctively(P0.05).CONCLUSION Gengning pill can regulate the functions of gonad axis and thyroid gland axis of ovariectomized rats.The result of this experiment indicates that Gengning pill can treat perimenopausal syndrome effectively.