Objective To find out the muhidrug resistant situation of tuberculosis patients in Sichuan and offer foundationfor the effective treatment.Methods By combining the test of drug sensitiveness and review survey method,using SPSS12.0 to analyze the factors and the multidrug resistant ratio and order.Results The total multidrug resistant ratio of tuberculosisin Sichuan is 33.60%;there are obvious differences divided by gender,region and so on;the main muhidrug resistant are val-bellite and rifampicin.Conclusion It is still serious of muhidrug resistant of tuberculosis patients in Sichuan and needs effect-tive treatment.