The appearances and evaluation of 99Tcm-MDP accumulation in non-osseous tissue: report of 497 cases

Objective: To evaluate the clinical significance of 99Tcm-MDP accumulation in non-osseous tissue. Materials and Methods: 6602 99Tcm-MDP bone scans were reviewed and 99Tcm-MDP accumulations in non-osseous tissue were distinguished. Results: 99Tcm-MDP accumulations were detected in 497 bone scans. Diffuse accumulations were detected in limbs, chest and abdomen(malignant pleural effusion, 146, malignant seroperitoneum, 44, obstruction in circumfluence of vein or lymph, 120, hyperparathyroidism, 3, metastatic tumor in liver, 20). Regional accumulations were detected in various tumors of defferent locations(107 cases, 1 was benign and the others were malignant), myocarditis(1), infarct in brain(1), rhabdomyositis(1), regional soft tissue after bone fracture(16) and recent operation(18), scar in skin(7) and stoma caused by operation(13). In all the lesions above, benign lesions were 33% while malignant lesions 67%. Conclusion: To distinguish the 99Tcm-MDP accumulation in non-osseous tissue is helpful to the analysis of bone scan and can offer some valuable information.