A new phenotype of asthma: chest tightness as the sole presenting manifestation

The typical symptoms of asthma are recurrent episodes of wheezing, breathlessness, chest tightness, and coughing, particularly at night. Apart from these classic features, some patients present with atypical symptoms, such as cough variant asthma with chronic cough as the only symptom. In this letter, we present a new group of asthma patients with chest tightness as their sole presenting manifestation. These patients are likely to be misdiagnosed. We believe that these cases represent a new clinical variant of asthma: chest tightness variant asthma (CTVA).