淋巴系统
2019年冠状病毒病(COVID-19)
医学
人口
严重急性呼吸综合征冠状病毒2型(SARS-CoV-2)
认知
内科学
精神科
疾病
脑脊液
环境卫生
传染病(医学专业)
作者
Lin Wang,Zhi Zhang,Xiao Liang,Yao Wang,Yuan Cao,Lu Meng,Fuqing Zhou
出处
期刊:iScience
[Elsevier]
日期:2024-01-01
卷期号:27 (1): 108647-108647
标识
DOI:10.1016/j.isci.2023.108647
摘要
Central nervous sequelae are often reported in recovered patients with COVID-19. It is not clear whether recovered COVID-19 patients have glymphatic impairment and clinical correlation. In this study, we demonstrated that mild COVID-19 patients experienced asymmetric bilateral glymphatic function decline after four months of recovery, and the decrease in glymphatic function was more obvious in older recovered patients. Our results further showed that recovered patients with right-sided glymphatic dysfunction experienced a greater proportion of cognitive decline (MoCA score <26) than patients with left-sided glymphatic dysfunction. With COVID-19 infection over 90% of the general population currently, future studies of cognitive disorders in the older population should consider the impact of COVID-19 infection.
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