自噬
细胞生物学
PI3K/AKT/mTOR通路
自噬体
衰老
化学
贝肯1
生物
雷帕霉素的作用靶点
基因敲除
信号转导
细胞凋亡
生物化学
作者
Kyeong Eun Yang,Soo-Bin Nam,Minsu Jang,Junsoo Park,Ga-Eun Lee,Yong‐Yeon Cho,Byeong‐Churl Jang,Cheol‐Jung Lee,Jong‐Soon Choi
标识
DOI:10.1016/j.jgr.2022.11.004
摘要
Rb2 reverses cellular senescence by activating autophagy via the AMPK-mTOR pathway and induction of DRAM2, suggesting that Rb2 might have potential value as an antiaging agent.
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