Advancing Metal–Organic Framework Designs for Room-Temperature Chemiresistive Gas Sensors

Metal–organic frameworks (MOFs) represent a versatile class of porous reticular materials whose structures and properties can be precisely tailored for targeted applications. A prominent example of such an application is the chemiresistive sensing of gases, where MOFs exhibit robust responses even at room temperature, thereby demonstrating their potential for practical utilization. This feature article reviews the development of the design criteria that are crucial for the optimization of MOFs as room-temperature chemiresistors. To highlight key advancements in this field, we categorize these materials into three distinct groups to (1) 2D conductive MOFs, (2) composites of MOFs with other materials, and (3) MOF-on-MOF architectures. The representative achievements from each group are discussed to demonstrate research progress in the construction of these innovative materials and their performance in gas sensing. Special emphasis is placed on the MOF-on-MOF materials, underscoring their role as pioneering smart materials for targeted application.