Innovation of 6-sulfonamide-2H-chromene derivatives as antidiabetic agents targeting α-amylase, α-glycosidase, and PPAR-γ inhibitors with in silico molecular docking simulation

A new series of 2-imino or 2-oxo-2 H -chromene-6-sulfonamide derivatives 2–9 were designed and synthesized and evaluated for anti-diabetic activity.