胸腺基质淋巴细胞生成素
干细胞因子
脱颗粒
促炎细胞因子
免疫学
化学
单克隆抗体
体内
抗体
炎症
生物
受体
细胞生物学
造血
干细胞
生物化学
生物技术
作者
Miles Murphy,Laura Vitale,Thomas J. O’Neill,Deena M. Maurer,Linda Malenchek,Andrea Crocker,Colleen Patterson,Laura Mills‐Chen,Virginia Saley,Nicole M. Antczak,James M. Boyer,Kelly M. McManus,Noe Rico Montanari,Russell A. Hammond,J. Goldstein,Lawrence J. Thomas,Tibor Keler,Diego Alexander Garzón Alvarado
出处
期刊:Allergy
[Wiley]
日期:2025-02-20
卷期号:80 (11): 3115-3126
被引量:4
摘要
CDX-622 is a potent inhibitor of MCs through the neutralization of SCF and effectively blocks Type 2 inflammatory responses driven by TSLP. Dual inhibition of these cytokines may lead to improved clinical outcomes in certain inflammatory disorders.
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