Treatment of Advanced or Metastatic Urothelial Cancer

Today, EV combined with pembrolizumab sets a new standard of care in medical treatment of a/mUC patients. Compared to platinum-based therapy, EV plus pembrolizumab doubled the overall survival probability and reported a median OS of 31.5 months, which is a new hallmark of palliative medical treatment in this disease. This novel therapy in combination with molecular therapies, novel devices, and molecular markers offers a great opportunity for the next step in medical development in localized UC, and its clinical applicability is being investigated in ongoing studies.