One-Year Outcomes After Amulet or Watchman Device for Percutaneous Left Atrial Appendage Closure: A Prespecified Analysis of the SWISS-APERO Randomized Clinical Trial

HomeCirculationVol. 149, No. 6One-Year Outcomes After Amulet or Watchman Device for Percutaneous Left Atrial Appendage Closure: A Prespecified Analysis of the SWISS-APERO Randomized Clinical Trial No AccessResearch ArticleRequest AccessFull TextAboutView Full TextView PDFView EPUBSections ToolsAdd to favoritesDownload citationsTrack citationsPermissions ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toNo AccessResearch ArticleRequest AccessFull TextOne-Year Outcomes After Amulet or Watchman Device for Percutaneous Left Atrial Appendage Closure: A Prespecified Analysis of the SWISS-APERO Randomized Clinical Trial Roberto Galea, Nicolas Meneveau, Federico De Marco, Adel Aminian, Dik Heg, Konstantina Chalkou, Christoph Gräni, Frederic Anselme, Anna Franzone, Pascal Vranckx, Urs Fischer, Francesco Bedogni, Lorenz Räber and Marco Valgimigli Roberto GaleaRoberto Galea https://orcid.org/0000-0002-2492-9960 Departments of Cardiology (R.G., C.G., L.R., M.V.), CTU Bern, University of Bern, Switzerland. , Nicolas MeneveauNicolas Meneveau https://orcid.org/0000-0002-1017-0463 Besancon University Hospital, University of Burgundy Franche-Comté, Besancon, France (N.M.). , Federico De MarcoFederico De Marco https://orcid.org/0000-0003-3554-6938 Department of Cardiology, Monzino Cardiology Center, Milan, Italy (F.D.M.). , Adel AminianAdel Aminian https://orcid.org/0000-0002-4667-9181 Department of Cardiology, Centre Hospitalier Universitaire de Charleroi, Belgium (A.A.). , Dik HegDik Heg https://orcid.org/0000-0002-8766-7945 Bern University Hospital, and Department of Clinical Research (D.H., K.C.), CTU Bern, University of Bern, Switzerland. , Konstantina ChalkouKonstantina Chalkou https://orcid.org/0000-0001-9718-021X Bern University Hospital, and Department of Clinical Research (D.H., K.C.), CTU Bern, University of Bern, Switzerland. , Christoph GräniChristoph Gräni https://orcid.org/0000-0001-6029-0597 Departments of Cardiology (R.G., C.G., L.R., M.V.), CTU Bern, University of Bern, Switzerland. , Frederic AnselmeFrederic Anselme https://orcid.org/0000-0002-2130-9790 Department of Cardiology, University Hospital of Rouen, France (F.A.). , Anna FranzoneAnna Franzone Department of Advanced Biomedical Sciences, University Federico II University, Naples, Italy (A.F.). , Pascal VranckxPascal Vranckx https://orcid.org/0000-0002-1526-0652 Department of Cardiology and Critical Care Medicine, Hartcentrum Hasselt, Jessa Ziekenhuis, Hasselt, Belgium (P.V.). Faculty of Medicine and Life Sciences, Hasselt University, Belgium (P.V.). , Urs FischerUrs Fischer https://orcid.org/0000-0003-0521-4051 Neurology (U.F.), CTU Bern, University of Bern, Switzerland. , Francesco BedogniFrancesco Bedogni Department of Cardiology, IRCCS Policlinico San Donato, San Donato Milanese, Milan, Italy (F.B.). , Lorenz RäberLorenz Räber https://orcid.org/0000-0003-0824-3026 Departments of Cardiology (R.G., C.G., L.R., M.V.), CTU Bern, University of Bern, Switzerland. and Marco ValgimigliMarco Valgimigli Correspondence to: Marco Valgimigli, MD, PhD, Cardiocentro Ticino Institute and Università della Svizzera Italiana (USI), Via Tesserete 48, 6900, Lugano, Switzerland. Email E-mail Address: [email protected] https://orcid.org/0000-0002-4353-7110 Departments of Cardiology (R.G., C.G., L.R., M.V.), CTU Bern, University of Bern, Switzerland. Cardiocentro Ticino Institute and Università della Svizzera Italiana (USI), Lugano, Switzerland (M.V.). Originally published24 Oct 2023https://doi.org/10.1161/CIRCULATIONAHA.123.067599Circulation. 2024;149:484–486FootnotesThis work was presented as an abstract at TCT, October 23–26, 2023.For Sources of Funding and Disclosures, see page 486.Circulation is available at www.ahajournals.org/journal/circRegistration: URL: https://www.clinicaltrials.gov; Unique identifier: NCT03399851.Correspondence to: Marco Valgimigli, MD, PhD, Cardiocentro Ticino Institute and Università della Svizzera Italiana (USI), Via Tesserete 48, 6900, Lugano, Switzerland. Email marco.valgimigli@eoc.chREFERENCES1. Dukkipati SR, Holmes DR, Doshi SK, Kar S, Singh SM, Gibson D, Price MJ, Natale A, Mansour M, Sievert H, et al. Impact of peridevice leak on 5-year outcomes after left atrial appendage closure.J Am Coll Cardiol. 2022; 80:469–483. doi: 10.1016/j.jacc.2022.04.062CrossrefMedlineGoogle Scholar2. Banga S, Osman M, Sengupta PP, Benjamin MM, Shrestha S, Challa A, Zeb I, Kadiyala M, Mills J, Balla S, et al. CT assessment of the left atrial appendage post-transcatheter occlusion: a systematic review and meta analysis.J Cardiovasc Comput Tomogr. 2021; 15:348–355. doi: 10.1016/j.jcct.2020.12.003CrossrefMedlineGoogle Scholar3. Galea R, De Marco F, Aminian A, Meneveau N, Anselme F, Gräni C, Huber AT, Teiger E, Iriart X, Angelillis M, et al. Design and rationale of the SWISS-APERO randomized clinical Trial: comparison of Amplatzer Amulet vs Watchman device in patients undergoing left atrial appendage closure.J Cardiovasc Transl Res. 2021; 14:930–940. doi: 10.1007/s12265-020-10095-4CrossrefMedlineGoogle Scholar4. Galea R, De Marco F, Meneveau N, Aminian A, Anselme F, Gräni C, Huber AT, Teiger E, Iriart X, Babongo Bosombo F, et al. Amulet or Watchman device for percutaneous left atrial appendage closure: primary results of the SWISS-APERO randomized clinical trial.Circulation. 2022; 145:724–738. doi: 10.1161/CIRCULATIONAHA.121.057859LinkGoogle Scholar5. Lakkireddy D, Thaler D, Ellis CR, Swarup V, Gambhir A, Hermiller J, Nielsen-Kudsk JE, Worthley S, Nair D, Schmidt B, et al. 3-Year outcomes from the Amplatzer Amulet Left Atrial Appendage Occluder randomized controlled trial (Amulet IDE).JACC Cardiovasc Interv. 2023; 16:1902–1913. doi: 10.1016/j.jcin.2023.06.022CrossrefMedlineGoogle Scholar eLetters(0)eLetters should relate to an article recently published in the journal and are not a forum for providing unpublished data. Comments are reviewed for appropriate use of tone and language. Comments are not peer-reviewed. Acceptable comments are posted to the journal website only. Comments are not published in an issue and are not indexed in PubMed. Comments should be no longer than 500 words and will only be posted online. References are limited to 10. Authors of the article cited in the comment will be invited to reply, as appropriate.Comments and feedback on AHA/ASA Scientific Statements and Guidelines should be directed to the AHA/ASA Manuscript Oversight Committee via its Correspondence page.Sign In to Submit a Response to This Article Previous Back to top Next FiguresReferencesRelatedDetails February 6, 2024Vol 149, Issue 6 Advertisement Article InformationMetrics © 2023 American Heart Association, Inc.https://doi.org/10.1161/CIRCULATIONAHA.123.067599PMID: 37875064 Originally publishedOctober 24, 2023 Keywordsatrial fibrillationischemic strokeleft atrial appendage closurePDF download Advertisement