双稳态
视紫红质
视蛋白
多谐振荡器
颜料
生物物理学
G蛋白偶联受体
化学
生物
材料科学
生物化学
物理
受体
光电子学
有机化学
量子力学
电压
视网膜
作者
Hisao Tsukamoto,Akihisa Terakita
摘要
Rhodopsin and related opsin-based pigments, which are photosensitive membrane proteins, have been extensively studied using a wide variety of techniques, with rhodopsin being the most understood G protein-coupled receptor (GPCR). Animals use various opsin-based pigments for vision and a wide variety of non-visual functions. Many functionally varied pigments are roughly divided into two kinds, based on their photoreaction: bistable and monostable pigments. Bistable pigments are thermally stable before and after photo-activation, but monostable pigments are stable only before activation. Here, we review the diversity of bistable pigments and their molecular characteristics. We also discuss the mechanisms underlying different molecular characteristics of bistable and monostable pigments. In addition, the potential of bistable pigments as a GPCR model is proposed.
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