医学
免疫系统
肿瘤微环境
上皮性卵巢癌
巨噬细胞
卵巢癌
免疫监视
HMOX1型
上皮
癌症研究
癌症
免疫学
病理
内科学
生物
遗传学
血红素
生物化学
血红素加氧酶
体外
酶
作者
Yi Liu,Lijun Jiang,Hongfang Liu,Li Chen,Lei Guo,Jun Ge,Xinyi Zhang,Jing Li,Wei Gong
标识
DOI:10.1097/js9.0000000000002829
摘要
Overall, we proposed and validated two strategies targeting HMOX1 to improve the efficacy of PD-1 inhibitors, and confirmed that HMOX1, TGF-β1, SPP1, FOLR2, and C1QC could be used to construct models predicting the efficacy of immune checkpoint inhibitors.
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