Innovative supramolecular magnetic magnesium-aluminum LDHs-decorated-carboxymethylcellulose for doxorubicin uptake from aqueous solutions

Doxorubicin drug (DOX) is well-characterized by its high chemical stability with minimum ability to biodegrade. It has been recently characterized as a pollutant in wastewaters. Therefore, the current investigation is devoted to explore the potential recovery of DOX pollutant onto a newly assembled nanocomposite from the combination of carboxymethylcellulose and magnetite with magnesium/aluminum double layered hydroxide (CMC@Fe 3 O 4 @MgAl-LDHs). Fe, O, C, Mg and Al elements were detected in this nanocomposite providing 44.78, 38.81, 9.12, 4.02 and 3.27%, respectively. The implementation of CMC@Fe 3 O 4 @MgAl-LDHs in sportive removal of DOX was monitored under numerous impacting conditions including pH (2.0 – 11.0), reaction time (2-60 min), nanocomposite dosage (2-60 mg), ionic strength via NaCl (10.0-100.0 mg), DOX initial concentration (1.0-20.0 mg.L -1 ) and reaction temperature (25-60 o C). The pHpzc of CMC@Fe 3 O 4 @MgAl-LDHs was detected as 5.8 to favoring high adsorptive capture values of DOX near this pH condition. CMC@Fe 3 O 4 @MgAl-LDHs exhibited excellent stability toward regeneration for five consecutive cycles providing 90.0-96.0%. Moreover, CMC@Fe 3 O 4 @MgAl-LDHs exhibited excellent removal capability of DOX from real waters up to 95.0-96.5 % (tap water), 95.5-96.1 % (wastewater) and 81.0-83.9 (sea water). Therefore, it could be concluded from the provided data that the investigated CMC@Fe 3 O 4 @MgAl-LDHs is a valid and promising adsorbent with lauded potential for significant implementation in DOX recovery from real wastewaters providing high capability and performance with excellent efficiency. Finally, the outcomes from this study approved and lauded the high significance of CMC@Fe 3 O 4 @MgAl-LDHs owing to its practical potential in real water treatment based on its high adsorption efficiency, regenerability, biodegradability. • Synthesis a novel supramolecular nanocomposite from Fe 3 O 4 , MgAl-LDH and CMC, • The TEM analysis referred to identified particles size in the range 5.45 – 15.29 nm. • The point of zero charge on this nanocomposite was identified at pH 5.8. • Excellent regeneration of CMC@Fe 3 O 4 @MgAl-LDH for five consecutive cycles providing 90.0-96.0%. • DOX removal from contaminated tap and wastewater samples yielding 95.0-96.5 %.