High-Dimensional Single-Cell Mapping of Central Nervous System Immune Cells Reveals Distinct Myeloid Subsets in Health, Aging, and Disease

(Immunity 48, 380–395; February 20, 2018) In the version of this paper published online, the URLs provided for the author-deposited data was incorrect. In the STAR Methods Key Resources Table, the entries in the section “Deposited Data” have been changed as shown below. In the STAR Methods section “Data and Software Availability,” the paragraph has been corrected to read, “Mass cytometry data of CNS leukocytes from C57BL/6 adult, geriatric and EAE mice (https://community.cytobank.org/cytobank/experiments/69323) as well as from 4-month-old APP/PS1 and littermate control mice (https://community.cytobank.org/cytobank/experiments/69324) are available online.” The URLs have been corrected online. The authors regret this error.Tabled 1Deposited DataCyTOF data from C57BL/6 miceThis paperhttps://community.cytobank.org/cytobank/experiments/69323CyTOF data from APP/PS1 mice and littermate controlsThis paperhttps://community.cytobank.org/cytobank/experiments/69324 Open table in a new tab High-Dimensional Single-Cell Mapping of Central Nervous System Immune Cells Reveals Distinct Myeloid Subsets in Health, Aging, and DiseaseMrdjen et al.ImmunityFebruary 6, 2018In BriefIt has been challenging to map leukocytes in the brain, particularly during pathology. Mrdjen et al. combine high-dimensional single-cell cytometry with fate mapping to capture the immune landscape of the brain. They identify different subsets of myeloid cells and the phenotypic changes in CNS immune cells during aging and in models of Alzheimer’s disease and multiple sclerosis. Full-Text PDF Open Archive