医学
冠状动脉疾病
急性冠脉综合征
抗血栓
肾脏疾病
血运重建
重症监护医学
内科学
心脏病学
随机对照试验
经皮冠状动脉介入治疗
肾功能
人口
心肌梗塞
环境卫生
作者
Marco Di Mauro,Vincenzo Fiorentini,Raffaella Mistrulli,Francesco Antonio Veneziano,Leonardo De Luca
标识
DOI:10.31083/j.rcm2302049
摘要
Coronary artery disease (CAD) and chronic kidney disease (CKD) may reciprocally influence each other. Patients with CAD and CKD have an increased risk of both ischemic and hemorrhagic events.In the present review, we summarize the existing literature focusing on the relationship between kidney dysfunction and acute coronary syndromes (ACS) in terms of risk factors, complications, and prognosis. We discuss also about the best evidence-based strategies to prevent deterioration of renal function in patients with CAD.Patients with CKD less frequently receive an invasive management (percutaneous or surgical revascularization) and potent antithrombotic drugs. Nevertheless, recent evidence suggests they would benefit from a selective invasive management, especially in case of ACS.Patients with CKD and CAD represent a challenging population, more randomized controlled trials and meta-analyses are needed to better define the best therapeutic strategy during an ACS episode.
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