Change of serum procalcitonin and C reactive protein and their correlation with prognosis in patients with intracranial infection

Objective To explore the change of serum procalcitonin and C reactive protein and assessing their prognostic value in patients with intracranial infection.Methods Fifty-one patients with intracranial infection from January 2009 to December 2012 in our hospital were selected as the study subjects(the study group),and 34 healthy individuals at the same time were selected as the control group.Procalcitonin and C reactive protein in serum were determined.The 51 patients were divided randomly into the cure group,the improved group and the worse/death group.The relationship between procalcitonin,C reactive protein and prognosis were analyzed.Results Compared with the control group,procalcitonin and C reactive protein in serum were significantly increased in the study group(P0.05).Compared with the worse/death group,procalcitonin and C reactive protein in serum significantly reduced in the cure group and the improved group(P0.05).Procalcitonin and C reactive protein in the cure group significantly reduced than that in the improved group(P0.05).Conclusion Serum procalcitonin and C reactive protein level can be used as auxiliary indexes for clinical diagnosis and prognosis of intracranial infection.