Analysis on effect of coagulation function detection in patients with liver cirrhosis

Objective To analyze the effect of coagulation function changes depending on the degree of liver damage in patients with liver cirrhosis. Methods To assay prothrombin time (PT), partial thromboplastin time (APTT), Thrombin time (TT) and Fibrinogen (FIB) in liver cirrhosis group (50 cases) and control group (40 cases). Results PT, APTT and TT of liver cirrhosis group were better than that in control group (P 0.01), and the FIB was distinctly dropped than that in control group (P 0.05). PT, APTT, TT and FIB of compensated liver cirrhosis group were better than that in decompensated liver cirrhosis group (P 0.01). Conclusions The coagulation indicators can objectively and accurately evaluate the coagulation function of patients with liver cirrhosis, which can find earlier coagulation mechanism disorders caused by liver disease. It has important significance to rescue and treat patients with liver cirrhosis when hemorrhage happened.