The Fundamental Study for Development of Noninvasive Monitor of Blood Pressure

In the case of hypertension patients, monitoring of change in blood pressure and the strain level of the sympathetic nervous system is essentially required. In this study, a method to estimate the systolic and diastolic blood pressure from time-domain parameters of the heart rate variability is proposed. Using this method, it may be possible to monitor blood pressure continuously without posture restriction for a prolonged period of time.Systolic blood pressure (SBP) and diastolic blood pressure (DBP) were estimated from time series of RR intervals during change in posture and compared with those monitored with a portable digital sphygmomanometer. From analysis of data collected on normal subject aged 21-75 years, it was found that DBP and SBP were able to estimate from the heart rate, the parameters evaluating the autonomic function or the autonomic regularity and the age.