Recurrence in Benign Paroxysmal Positional Vertigo: A Large, Single-Institution Study

医学 良性阵发性位置性眩晕 耳科 梅尼埃病 神经学 眩晕 外科 病因学 耳鸣 糖尿病 回顾性队列研究 疾病 耳鼻咽喉科 儿科 内科学 听力学 内分泌学 头颈外科
作者
Alexander L. Luryi,Juliana Lawrence,Dennis I. Bojrab,Michael J. LaRouere,Seilesh C. Babu,John J. Zappia,Eric W. Sargent,Eleanor Chan,Ilka C. Naumann,Robert Hong,Christopher A. Schutt
出处
期刊:Otology & Neurotology [Lippincott Williams & Wilkins]
卷期号:39 (5): 622-627 被引量:46
标识
DOI:10.1097/mao.0000000000001800
摘要

Objective: To report rates of recurrence in benign paroxysmal positional vertigo (BPPV) and associated patient and disease factors. Study Design: Retrospective chart review. Setting: Single high-volume otology practice. Patients: Patients diagnosed with BPPV from 2007 to 2016 with documented resolution of symptoms. Intervention: Diagnostic and particle repositioning maneuvers for BPPV. Main Outcome Measures: BPPV recurrence, time to recurrence, and ear(s) affected at recurrence. Results: A total of 1,105 patients meeting criteria were identified. Of this population, 37% had recurrence of BPPV in either ear or both ears. Overall same-ear recurrence rate was 28%; 76% of recurrences involved the same ear(s) as initial presentation. Recurrences that occurred after longer disease-free intervals were more likely to involve the opposite ear than early recurrences ( p = 0.02). Female sex (40.4% versus 32.7%, p = 0.01) and history of previous BPPV (57.5% versus 32.4%, p < 0.0005) were associated with increased risk of recurrence, while history of Menière's disease, diabetes mellitus, and traumatic etiology were not. Approximately, half (56%) of recurrences occurred within 1 year of resolution. Conclusions: A large single-institution study of recurrence in BPPV is presented along with Kaplan–Meier disease-free survival curves. Female sex and history of previous BPPV were associated with increased recurrence, while previously suspected risk factors for recurrence including history of Menière's disease, diabetes, and trauma were not. Remote recurrence is more likely to involve the contralateral ear than early recurrence. These data solidify the expected course of treated BPPV allowing for improved clinical care and patient counseling.
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