Prevalence depression – Anxiety and impact on quality of life, asthma control and asthma severity in adult patients with asthma

We examined the prevalence of depression and anxiety, and impact of depression and anxiety on quality of life, and treatment response of disease in patients with asthma. Demographic data, smoking, allergy, atopy, additional diseases, age started asthma, age diagnosed asthma, and body mass index was (BMI) calculated. Hospital-Anxiety Depression Scale (HADS), Asthma Quality of Life Questionnaires (AQLQ) in the subjects were evaluated. The sample consisted of 414 subjects (73% female) with a mean age of 47,6±13,8 years. Regarding chronic severity, 9,8% were intermittent, 63,2% mild persistent, 24,4% moderate persistent, and 2,6% severe persistent. Furthermore, 44,1% of the subjects were controlled asthma, 47,9% were partly controlled,%8 were uncontrolled. Rates of physician-diagnosed depression and anxiety were 10,4% and 2,9%. Regarding HADS, anxiety score was ≥10 in 37,4% and depression score ≥7 in 50,2% of the subjects. Prevalence of physician-diagnosed depression was significantly higher in women. HADS depression score was significantly higher in women (p It suggests that depression and anxiety are associated with worse asthma control and quality of life. Physicians should consider depression and anxiety in patients with worse controlled asthma and quality of life in spite of optimal therapy for asthma.