A feasible method for clinical delivery verification and dose reconstruction in tomotherapy

断层治疗 成像体模 迭代重建 计算机科学 探测器 医学影像学 剂量学 医学物理学 核医学 计算机视觉 人工智能 医学 放射治疗 放射科 电信
作者
Jeff Kapatoes,G. Olivera,K Ruchala,Jennifer B. Smilowitz,Paul Reckwerdt,Thomas Rockwell Mackie
出处
期刊:Medical Physics [Wiley]
卷期号:28 (4): 528-542 被引量:98
标识
DOI:10.1118/1.1352579
摘要

Delivery verification is the process in which the energy fluence delivered during a treatment is verified. This verified energy fluence can be used in conjunction with an image in the treatment position to reconstruct the full three‐dimensional dose deposited. A method for delivery verification that utilizes a measured database of detector signal is described in this work. This database is a function of two parameters, radiological path‐length and detector‐to‐phantom distance, both of which are computed from a CT image taken at the time of delivery. Such a database was generated and used to perform delivery verification and dose reconstruction. Two experiments were conducted: a simulated prostate delivery on an inhomogeneous abdominal phantom, and a nasopharyngeal delivery on a dog cadaver. For both cases, it was found that the verified fluence and dose results using the database approach agreed very well with those using previously developed and proven techniques. Delivery verification with a measured database and CT image at the time of treatment is an accurate procedure for tomotherapy. The database eliminates the need for any patient‐specific, pre‐ or post‐treatment measurements. Moreover, such an approach creates an opportunity for accurate, real‐time delivery verification and dose reconstruction given fast image reconstruction and dose computation tools.

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