抗菌剂
水杨醛
卡那霉素
抗真菌
制霉菌素
联氨(抗抑郁剂)
细菌
化学
席夫碱
药物化学
生物
微生物学
有机化学
立体化学
抗生素
生物化学
遗传学
作者
Mele Jesmin,Md. Liakot Ali,M. S. Salahuddin,M. Rowshanul Habib,Jahan Ara Khanam
出处
期刊:Mycobiology
[Informa]
日期:2008-01-01
卷期号:36 (1): 70-70
被引量:30
标识
DOI:10.4489/myco.2008.36.1.070
摘要
The antibacterial and antifungal activities of three schiff bases were evaluated against some pathogenic bacteria and fungi. Parallel experiments were also carried out with standard drugs (Kanamycin for bacteria and Nystatin for fungi). Two compounds [N-(1-phenyl-2-hydroxy-2phenylethylidine)-2',4' dinitrophenyl hydrazine, abbreviated as PDH and N-(2-hydroxy benzylidine)-2'-hydroxy imine, abbreviated as HHP] showed significant antimicrobial activities. The rest one [N-(1-phenyl 2-hydroxy-2 phenyl ethylidine) 2'-hydroxy phenyl imine, abbreviated as PHP] showed moderate activity. All these three compounds were found to possess pronounced cytotoxic effect. These compounds can be considered as potent antimicrobial agents.
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