Assessment of hepatic microvascular changes in liver cirrhosis by 320 row CT perfusion imaging

Objective To evaluate the value of 320 row CT perfusion imaging in assessing the hemodynamic changes of cirrhosis. Methods All of the patients in cirrhosis group and control group were selected to perform hepatic perfusion by a 320 row CT scanner. The parameters of hepatic perfusion were calculated, including portal vein perfusion(PVP), hepatic artery perfusion(HAP) and hepatic perfusion index(HPI); and then, total hepatic perfusion(THBP) was calculated. Results Compare to the control group, THBP and PVP of the cirrhosis group showed a trend of decline(P 0.05), and HAP and HPI of the cirrhosis group showed a trend of rise(P 0.05). There were significant differences in all parameters between the two groups(P 0.05). Conclusions It is an effective method to apply 320 row CT perfusion for assessing hepatic microvascular changes in liver cirrhosis, and which can serve as a new method for clinical research.