医学
羟脯氨酸
肌酐
更年期
骨重建
骨吸收
内科学
骨矿物
内分泌学
碱性磷酸酶
骨质疏松症
绝经后骨质疏松症
骨密度
绝经后妇女
尿钙
泌尿科
化学
酶
生物化学
作者
Shen L,Jiafang Du,Jun Yang
出处
期刊:Chinese journal of integrated traditional and Western medicine
日期:1994-09-01
卷期号:14 (9): 515-8
被引量:3
摘要
The effect of Bushen Migu Ye (BSMGY) on preventing the bone loss in postmenopausal women was observed. 43 healthy women with the menopause within 5 years were randomly divided into the treated and control groups, which were basically similar in age and menopausal time. BSMGY and Rhizoma Dioscoreae decoction was given orally in two groups. Some biochemical parameters related to bone metabolism, serum estradiol and forearm bone density were taken before and after treatment. The results showed that 5 months after BSMGY treatment, the ulnar and radial bone mineral content was higher than that of pretreatmental value (P < 0.05), while in control group this index was continually decreased. The change in bone density were also significant different (P < 0.05). It seems that BSMGY is able to prevent the bone loss in postmenopausal women. In the treated group, ratio of fasting urinary calcium and hydroxyproline to creatinine was lower than that of before treatment and the control group (P < 0.05); the concentration of serum alkaline phosphatase had no significant difference (P < 0.05). This preliminary study suggested that one of the therapeutic mechanism of BSMGY was probably due to declining of bone resorption, without affecting the bone formation in postmenopausal women.
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