[Analysis of 14 cases of melanosis caused by 1, 8-dinitronaphthalene and 1, 8-diaminonaphthalene].

14 workers in the 1, 8-diaminonaphthalene workshop of a chemical company in Nantong City had symptoms or signs of varying degrees of pruritus and pigmentation of the face, neck and waist. Pathological examination of skin biopsies showed hyperkeratosis, the basal cells were liquefied and denatured. Seven workers were eventually diagnosed with occupational melanosis. To explore the causes of occupational melanosis caused by exposure to 1, 8-dinitronaphthalene and 1, 8-diaminonaphthalene, and to provide reference for the prevention and treatment of occupational melanosis in the future, this paper reported 14 cases of melanosis in the skin of workers in chemical industry.南通市某化工有限公司1, 8-二氨基萘车间14名工人出现不同程度皮肤瘙痒、面颈腰部深浅不一色素沉着等症状或体征，皮肤活检病理检查示角化过度、基底细胞液化变性，最终有7名工人被确诊为职业性黑变病。为探索接触1, 8-二硝基萘和1, 8-二氨基萘导致职业性黑变病的原因，为今后职业性黑变病的防治提供参考，本文就化工行业14例作业工人皮肤黑变病进行报道。.