回转率
前列腺
磁共振成像
核医学
动态增强MRI
核磁共振
翻转角度
射频线圈
医学
生物医学工程
物理
材料科学
放射科
癌症
内科学
电压
量子力学
作者
Ante Zhu,Matthew Tarasek,Yaping Hua,Eric Fiveland,Stephan E. Maier,Yousef Mazaheri,Maggie Fung,Carl‐Fredrik Westin,Desmond Yeo,Filip Szczepankiewicz,Clare M. Tempany,Oğuz Akın,Thomas K.F. Foo
摘要
To demonstrate the technical feasibility and the value of ultrahigh-performance gradient in imaging the prostate in a 3T MRI system.In this local institutional review board-approved study, prostate MRI was performed on 4 healthy men. Each subject was scanned in a prototype 3T MRI system with a 42-cm inner-diameter gradient coil that achieves a maximum gradient amplitude of 200 mT/m and slew rate of 500 T/m/s. PI-RADS V2.1-compliant axial T2 -weighted anatomical imaging and single-shot echo planar DWI at standard gradient of 70 mT/m and 150 T/m/s were obtained, followed by DWI at maximum performance (i.e., 200 mT/m and 500 T/m/s). In comparison to state-of-the-art clinical whole-body MRI systems, the high slew rate improved echo spacing from 1020 to 596 μs and, together with a high gradient amplitude for diffusion encoding, TE was reduced from 55 to 36 ms.In all 4 subjects (waist circumference = 81-91 cm, age = 45-65 years), no peripheral nerve stimulation sensation was reported during DWI. Reduced image distortion in the posterior peripheral zone prostate gland and higher signal intensity, such as in the surrounding muscle of high-gradient DWI, were noted.Human prostate MRI at simultaneously high gradient amplitude of 200 mT/m and slew rate of 500 T/m/s is feasible, demonstrating that improved gradient performance can address image distortion and T2 decay-induced SNR issues for in vivo prostate imaging.
科研通智能强力驱动
Strongly Powered by AbleSci AI