Hypoxia‐Responsive Photosensitizer Targeting Dual Organelles for Photodynamic Therapy of Tumors (Small 1/2023)

SmallVolume 19, Issue 1 2370006 Back CoverFree Access Hypoxia-Responsive Photosensitizer Targeting Dual Organelles for Photodynamic Therapy of Tumors (Small 1/2023) Yuqi Tang, Yuqi Tang Institute of Advanced Materials and School of Chemistry and Chemical Engineering, Southeast University, Nanjing, 211189 P. R. ChinaSearch for more papers by this authorXing Wang, Xing Wang Institute of Advanced Materials and School of Chemistry and Chemical Engineering, Southeast University, Nanjing, 211189 P. R. ChinaSearch for more papers by this authorGuanqun Zhu, Guanqun Zhu Institute of Advanced Materials and School of Chemistry and Chemical Engineering, Southeast University, Nanjing, 211189 P. R. ChinaSearch for more papers by this authorZhiyang Liu, Zhiyang Liu Institute of Advanced Materials and School of Chemistry and Chemical Engineering, Southeast University, Nanjing, 211189 P. R. ChinaSearch for more papers by this authorXu-Man Chen, Xu-Man Chen Institute of Advanced Materials and School of Chemistry and Chemical Engineering, Southeast University, Nanjing, 211189 P. R. ChinaSearch for more papers by this authorHari Krishna Bisoyi, Hari Krishna Bisoyi Advanced Materials and Liquid Crystal Institute and Chemical Physics Interdisciplinary Program, Kent State University, Kent, OH, 44242 USASearch for more papers by this authorXiao Chen, Xiao Chen Institute of Advanced Materials and School of Chemistry and Chemical Engineering, Southeast University, Nanjing, 211189 P. R. ChinaSearch for more papers by this authorXiaofei Chen, Xiaofei Chen Institute of Advanced Materials and School of Chemistry and Chemical Engineering, Southeast University, Nanjing, 211189 P. R. ChinaSearch for more papers by this authorYiyi Xu, Yiyi Xu Institute of Advanced Materials and School of Chemistry and Chemical Engineering, Southeast University, Nanjing, 211189 P. R. ChinaSearch for more papers by this authorJuping Li, Juping Li Institute of Advanced Materials and School of Chemistry and Chemical Engineering, Southeast University, Nanjing, 211189 P. R. ChinaSearch for more papers by this authorQuan Li, Quan Li Institute of Advanced Materials and School of Chemistry and Chemical Engineering, Southeast University, Nanjing, 211189 P. R. China Advanced Materials and Liquid Crystal Institute and Chemical Physics Interdisciplinary Program, Kent State University, Kent, OH, 44242 USASearch for more papers by this author Yuqi Tang, Yuqi Tang Institute of Advanced Materials and School of Chemistry and Chemical Engineering, Southeast University, Nanjing, 211189 P. R. ChinaSearch for more papers by this authorXing Wang, Xing Wang Institute of Advanced Materials and School of Chemistry and Chemical Engineering, Southeast University, Nanjing, 211189 P. R. ChinaSearch for more papers by this authorGuanqun Zhu, Guanqun Zhu Institute of Advanced Materials and School of Chemistry and Chemical Engineering, Southeast University, Nanjing, 211189 P. R. ChinaSearch for more papers by this authorZhiyang Liu, Zhiyang Liu Institute of Advanced Materials and School of Chemistry and Chemical Engineering, Southeast University, Nanjing, 211189 P. R. ChinaSearch for more papers by this authorXu-Man Chen, Xu-Man Chen Institute of Advanced Materials and School of Chemistry and Chemical Engineering, Southeast University, Nanjing, 211189 P. R. ChinaSearch for more papers by this authorHari Krishna Bisoyi, Hari Krishna Bisoyi Advanced Materials and Liquid Crystal Institute and Chemical Physics Interdisciplinary Program, Kent State University, Kent, OH, 44242 USASearch for more papers by this authorXiao Chen, Xiao Chen Institute of Advanced Materials and School of Chemistry and Chemical Engineering, Southeast University, Nanjing, 211189 P. R. ChinaSearch for more papers by this authorXiaofei Chen, Xiaofei Chen Institute of Advanced Materials and School of Chemistry and Chemical Engineering, Southeast University, Nanjing, 211189 P. R. ChinaSearch for more papers by this authorYiyi Xu, Yiyi Xu Institute of Advanced Materials and School of Chemistry and Chemical Engineering, Southeast University, Nanjing, 211189 P. R. ChinaSearch for more papers by this authorJuping Li, Juping Li Institute of Advanced Materials and School of Chemistry and Chemical Engineering, Southeast University, Nanjing, 211189 P. R. ChinaSearch for more papers by this authorQuan Li, Quan Li Institute of Advanced Materials and School of Chemistry and Chemical Engineering, Southeast University, Nanjing, 211189 P. R. China Advanced Materials and Liquid Crystal Institute and Chemical Physics Interdisciplinary Program, Kent State University, Kent, OH, 44242 USASearch for more papers by this author First published: 04 January 2023 https://doi.org/10.1002/smll.202370006AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat Graphical Abstract Photodynamic Therapy of Tumors In article number 2205440, Zhiyang Liu, Quan Li, and co-workers exploit the hypoxic properties of solid tumors to construct a hypoxia-responsive photosensitizer. When the non-fluorescent hypoxia-responsive photosensitizer enters the hypoxic tumors, it is reduced by the overexpressed azoreductase to generate the fluorescent photosensitizer with the aggregation-induced emission property, which can realize the fluorescence-activatable image-guided photodynamic therapy with dual-organelle (lipid droplets and lysosomes) targeting. Volume19, Issue1January 4, 20232370006 RelatedInformation