脂肪组织
白色脂肪组织
脂肪细胞
生物
发病机制
脂质代谢
计算生物学
生物信息学
细胞生物学
内分泌学
免疫学
出处
期刊:Endocrine, metabolic & immune disorders
[Bentham Science]
日期:2023-01-06
卷期号:23 (1): 12-20
被引量:1
标识
DOI:10.2174/1871530322666220827145241
摘要
Roles for adipose tissues in energy metabolism, health maintenance and disease onset have been established. Evidence indicates that white, brown and beige fats are quite different in terms of their cellular origin and biological characteristics. These differences are significant in targeting adipocytes to study the pathogenesis and prevention strategies of related diseases. The biotransformations of white, brown and beige fat cells constitute an intriguing topic worthy of further study, and the molecular mechanisms underlying the biotransformations of white, brown and beige fat cells remain to be elucidated. Hence, we herein collected evidence from studies on adipose tissue or adipocytes, and we extracted the structural features, biologic functions, and biotransformations of adipose tissue/adipocytes. The present review aimed to summarize the latest research progress and propose novel research directions with respect to adipose tissue and adipocytes. We posit that this work will provide new insights and opportunities in the effective treatment strategies for obesity, diabetes and other lipid-related diseases. It will also contribute to our knowledge of the basic biologic underpinnings of adipocyte biology.
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