Stevens-Johnson Syndrome, Toxic Epidermal Necrolysis: Macules, Papules, and Bullae

Objective: The objective of this discussion paper is to illuminate the importance of early identification and treatment of Stevens-Johnson Syndrome (SJS) and toxic epidermal necrolysis (TEN). SJS/TEN may occur as quickly as 4 days, more commonly 4 to 8 weeks after starting a new medication and early identification is essential. Methods: A review of literature revealed there is a lack of diagnostic awareness related to the clinical presentation and diverse populations at risk for this devastating syndrome. Results: A Boolean search was conducted, and six quantitative and qualitative research articles were discovered that indicate a knowledge disparity between “rash” versus SJS/TEN. Research indicates evidence-based best clinical practices for nurses and health care practitioners for assessment of risks, clinical presentation, and treatment. Conclusions: Prompt diagnosis and discontinuation of the suspected medication will reduce potential life-threatening sequelae.