ABSTRACT Background Use of coils during percutaneous coronary interventions (PCI) is often life‐saving and useful, although their off‐label use according to the instructions for use. Aims Evaluation of in‐hospital and long‐term outcomes of patients undergoing PCI with coil implantation for treating coronary perforation or closing coronary artery aneurysms/fistulas. Methods Among 245,652 PCIs performed in 17 high‐volume European centers, 143 patients (0.06%) undergoing coil implantation during PCI were finally included in the analysis. PCI strategy (coiling performed during coronary perforation vs. closing aneurysm/fistulas) and procedural devices used were collected. The primary outcome was technical success, defined as the successful sealing of coronary perforation or aneurysm/fistulas, and procedural success defined as technical success without in‐hospital major cardiovascular events (MACE). Long‐term MACE and mortality were also reported. Results The primary outcome occurred in 95.7% of cases, with no significant differences observed between the perforation and aneurysm/fistulas groups (94.5% vs. 100%, p = 0.19). Patients in the perforation group had a significantly lower rate of procedural success (83.5% vs. 96.6%, p = 0.01). Target lesion failure occurred in 11.4% of cases without differences between groups at a median follow‐up of 2 years. Conclusions Coils implantation during PCI is safe and feasible among patients treated for coronary perforations or closing aneurysms/fistulas.