医学
传统PCI
经皮
经皮冠状动脉介入治疗
放射科
成交(房地产)
介入心脏病学
外科
心脏病学
冠状动脉造影
多中心研究
梅德林
内科学
冠状动脉疾病
冠心病
作者
Enrico Cerrato,Giulio Piedimonte,Marco Franzino,Giorgio Marengo,Mario Bollati,Simone Zecchino,David Rutigliano,Francesco Soriano,Massimo Leoncini,Riccardo Mangione,Emanuele Sagazio,Marco Franzino,Francesco Jeva,Gian Paolo Ussia,Fernando Scudiero,Alfonso Franzè,Umberto Barbero,Dario Calderone,Annamaria Nicolino,Fabrizio Ugo
摘要
BACKGROUND: Use of coils during percutaneous coronary interventions (PCI) is often life-saving and useful, although their off-label use according to the instructions for use. AIMS: Evaluation of in-hospital and long-term outcomes of patients undergoing PCI with coil implantation for treating coronary perforation or closing coronary artery aneurysms/fistulas. METHODS: Among 245,652 PCIs performed in 17 high-volume European centers, 143 patients (0.06%) undergoing coil implantation during PCI were finally included in the analysis. PCI strategy (coiling performed during coronary perforation vs. closing aneurysm/fistulas) and procedural devices used were collected. The primary outcome was technical success, defined as the successful sealing of coronary perforation or aneurysm/fistulas, and procedural success defined as technical success without in-hospital major cardiovascular events (MACE). Long-term MACE and mortality were also reported. RESULTS: The primary outcome occurred in 95.7% of cases, with no significant differences observed between the perforation and aneurysm/fistulas groups (94.5% vs. 100%, p = 0.19). Patients in the perforation group had a significantly lower rate of procedural success (83.5% vs. 96.6%, p = 0.01). Target lesion failure occurred in 11.4% of cases without differences between groups at a median follow-up of 2 years. CONCLUSIONS: Coils implantation during PCI is safe and feasible among patients treated for coronary perforations or closing aneurysms/fistulas.
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