神经母细胞瘤RAS病毒癌基因同源物
克拉斯
赫拉
癌症
癌症研究
医学
外显子组测序
临床试验
突变
生物
肿瘤科
基因
遗传学
内科学
结直肠癌
作者
Sameek Roychowdhury,Matthew K. Iyer,Dan R. Robinson,Robert J. Lonigro,Yi-Mi Wu,Xuhong Cao,Shanker Kalyana‐Sundaram,Lee Sam,O. Alejandro Balbin,Michael J. Quist,Terrence R. Barrette,Jessica N. Everett,Javed Siddiqui,Lakshmi P. Kunju,Nora M. Navone,John C. Araujo,Patricia Troncoso,Christopher J. Logothetis,Jeffrey W. Innis,David C. Smith
标识
DOI：10.1126/scitranslmed.3003161
摘要
The mutations present in advanced cancers can be identified by integrative high-throughput sequencing to enable biomarker-driven clinical trials and, ultimately, treatment.
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