神经节
解剖
神经纤维瘤病
神经节细胞瘤
冠状面
医学
病理
生物
遗传学
细胞培养
神经母细胞瘤
作者
Peter Kannu,Munier Nour,Melita Irving,Jing Xie,D Loder,James C. K. Lai,Ovinu Kibria Islam,Jennifer MacKenzie,Ludwine Messiaen
标识
DOI:10.1111/j.1399-0004.2012.01882.x
摘要
Supporting Information The following Supporting information is available for this article: Fig. S1. (a) Chest radiograph – there is a large right paraspinal soft tissue opacity at the base of the right hemithorax, not in the middle mediastinum, as it is not silhouetting the right heart border. (b) Magnetic resonance imaging – axial T2 and coronal inversion recovery (IR) sequences reveals a posterior mediastinal soft tissue mass along the lateral margin of the spinal column. Coronal T1 post gadolinium sequence shows the mass to heterogeneously enhance. Involvement of multiple right-sided neural foramen is well seen on this sequence as well as on the Sagittal T2 sequence. (c) A cluster of maturing ganglion cells within the Schwannian stromal background. Note the increased nuclear to cytoplasmic ratio and multinucleation within these cells compared to a mature ganglion cell. (d) A mature ganglion cell stained with synaptophysin. Note the positive staining within the borders of the intracytoplasmic secretory vesicles at the periphery of the cell. Table S1. Summary of reported individuals with neurofibromatosis type I and ganglioneuroma Table S2. Summary of the 10 deep intronic neurofibromatosis type I mutations with mRNA effect reported so far Additional Supporting information may be found in the online version of this article. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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