作者
Meng-Ju Wu,Lei Shi,Juan Dubrot,Joshua Merritt,Vindhya Vijay,Ting-Yu Wei,Emily Kessler,Kira E Olander,Ramzi Adil,Amaya Pankaj,Krishna S. Tummala,Vajira Weeresekara,Yuanli Zhen,Qibiao Wu,Meiqi Luo,William Shen,María García-Beccaria,Mirian Fernandez-Vaquero,Christine Hudson,Sebastien Ronseaux,Yi Sun,Rodrigo Saad-Berreta,Russell W. Jenkins,Tong Wang,Mathias Heikenwalder,Cristina R. Ferrone,Lipika Goyal,Brandon Nicolay,Vikram Deshpande,Rahul M. Kohli,Hongwu Zheng,Robert T. Manguso,Nabeel Bardeesy
摘要
The efficacy of mutant IDH1 inhibition in a genetically engineered mouse model of cholangiocarcinoma is mediated by stimulation of cytotoxic T-cell function and derepression of TET2 in tumor cells, which epigenetically resensitizes tumor cells to IFNγ.
SYLH
冰魂
cdercder
nozero
卡卡西
非而者厚
昏睡的蟠桃
LMNg6n
失眠醉易
科研助手6
iNk
蛇虫鼠蚁
蓝调爱科研
ZhouYW
Accepted
故酒
粗心的绾绾
善良的剑通
pcr163
平常的毛豆
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