视觉光转导
Cone(正式语言)
生物物理学
神经科学
生物
级联
光学
细胞生物学
化学
视网膜
物理
计算机科学
算法
色谱法
作者
Gordon Fain,Alapakkam P. Sampath
标识
DOI:10.1007/s00424-021-02551-0
摘要
Cone photoreceptors provide the foundation of most of human visual experience, but because they are smaller and less numerous than rods in most mammalian retinas, much less is known about their physiology. We describe new techniques and approaches which are helping to provide a better understanding of cone function. We focus on several outstanding issues, including the identification of the features of the phototransduction cascade that are responsible for the more rapid kinetics and decreased sensitivity of the cone response, the roles of inner-segment voltage-gated and Ca2+-activated channels, the means by which cones remain responsive even in the brightest illumination, mechanisms of cone visual pigment regeneration in constant light, and energy consumption of cones in comparison to that of rods.
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