Trifluoromethylation of Allenes: An Expedient Access to α‐Trifluoromethylated Enones at Room Temperature

Abstract A silver(I) catalyzed regioselective trifluoromethylation of allenes using Langlois's salt (NaOSOCF 3 ) is demonstrated. This transformation enables direct expedient access to α‐trifluoromethylated acroleins, which are valuable synthons for a number of pharmaceuticals and agrochemicals containing vinyl‐CF 3 moieties. Versatility of this trifluoromethylation method has been established with good yield and excellent regioselectivity. Preliminary experiments and computational studies were carried out to elucidate the mechanistic insight of this protocol.