三七
鼠李糖
阿拉伯糖
多糖
半乳糖
抗氧化剂
化学
生物化学
甘露糖
氧化应激
食品科学
发酵
医学
病理
替代医学
木糖
作者
Shiling Feng,Haoran Cheng,Zhou Xu,Shican Feng,Ming Yuan,Yan Huang,Jinqiu Liao,Chunbang Ding
标识
DOI:10.1016/j.procbio.2019.01.007
摘要
Two novel polysaccharides, MRP5 and MRP5A, were obtained from the root of Panax notoginseng using column chromatography. Structure characterization suggested that MRP5A, with an average molecular weight of 11.38 × 104 Da, was composed of rhamnose (7.7%), arabinose (6.6%), glucose (69.8%) and galactose (15.9%). MRP5 had an average molecular weight of 9.16 × 104 Da and consisted of rhamnose (3.6%), arabinose (14.5%), glucose (51.2%) and galactose (29.7%). The results of methylation analysis and one-dimensional (1D) and two-dimensional (2D) nuclear magnetic resonance (NMR) spectra reveal that MRP5 contains repeating units of →3)-β-Glcp-(1→, →6)-β-Glcp-(1→, →3, 6)-Glcp-(1→, β-Glcp-(1→, →3)-β-Galp-(1→, →3, 6)-β-Galp-(1→, →3)-α-Rhap-(1→, →3)-α-Araf-(1→, and α-Araf-(1→ residues. MRP5 and MRP5A exhibited relatively low antioxidant abilities in vitro, but strongly protective effects against oxidative stress and lifespan extension effects in C. elegans. Overall, the present study indicated that MRP5 could be further investigated as a functional food for promoting healthspan.
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